Research Article

A Validated Stability-Indicating RP-HPLC Method for the Simultaneous Determination of Tenofovir, Emtricitabine, and a Efavirenz and Statistical Approach to Determine the Effect of Variables

Table 5

Recovery studies ( ).

DrugAmount added ( g/mL−1)Amount recovered ( g/mL−1)%Recovery ± SD; %RSD

ETC8080.0099.99 ± 0.05; 0.06
10099.6799.67 ± 0.15; 0.15
120119.3999.49 ± 0.06; 0.05
TDF9897.2599.23 ± 0.06; 0.06
122.5122.52100.02 ± 0.03; 0.03
147148.83101.25 ± 1.77; 1.19
EFV240244.27101.78 ± 0.83; 0.33
300302.92100.97 ± 0.18; 0.06
360364.12101.14 ± 0.98; 0.23