International Scholarly Research Notices

Review Article

The Mortality in Emergency Department Sepsis Score as a Predictor of 1-Month Mortality among Adult Patients with Sepsis: Weighing the Evidence

Table 2

Summary of included studies.


	Hermans et al., 2012 [23]	Lee et al., 2008 [24]	Vorwerk et al., 2009 [26]	Zhao et al., 2013 [25]

Study design	Retrospective cohort study	Prospective cohort study	Retrospective cohort study	Prospective cohort study

Study population	(i) One centre (tertiary) (ii) Adult ED patients (>18 years old)	(i) One centre (tertiary) (ii) Adult ED patients (≥15 years old)	(i) Two centres (one urban teaching and one district general) (ii) Adult ED patients (>16 years old)	(i) One centre (tertiary) (ii) Adult ED patients (>18 patients)
Study population	Sample size of 331 patients (i) Sepsis (62%) (ii) Severe sepsis (30%) (iii) Septic shock (4%)	Sample size of 525 patients (i) Sepsis (76%) (ii) Severe sepsis (19%) (iii) Septic shock (5%)	Sample size of 307 patients (i) No further information about categorisation by severity of sepsis	Sample size of 501 patients (i) Sepsis (64%) (ii) Severe sepsis (31%) (iii) Septic shock (5%)

Prognostic determinant	MEDS score	MEDS score	Abbreviated MEDS score	MEDS score

Comparator	C-reactive protein	C-reactive protein	—	C-reactive protein
	—	Procalcitonin	—	Procalcitonin
	Lactate	—	Lactate	—
	—	—	—	Interleukin-6
	—	—	—	MEDS + procalcitonin

Outcome	28-day mortality	5-day (early) and 6- to 30-day (late) mortality	28-day mortality	28-day mortality

ED: emergency department; MEDS score: Mortality in Emergency Department Sepsis score.