International Scholarly Research Notices

Review Article

The Mortality in Emergency Department Sepsis Score as a Predictor of 1-Month Mortality among Adult Patients with Sepsis: Weighing the Evidence

Critical appraisal of included studies*.


	Hermans et al., 2012 [23]	Lee et al., 2008 [24]	Vorwerk et al., 2009 [26]	Zhao et al., 2013 [25]

(A) C2010 Consensus Process for Levels of Evidence (LOE) for prognostic and retrospective studies	Retrospective (LOE P3)	Prospective (LOE P1)	Retrospective (LOE P3)	Prospective (LOE P1)

(B) Assessment of study quality based on the following factors:
(i) Was the sample of patients representative?	Yes	Yes	Yes	Yes
(ii) Were outcomes measured in the same (preferably blinded) objective way in both groups?	No	No	Yes	Yes
(iii) Were known confounders identified and appropriately controlled for?	Yes	Yes	No	Yes
(iv) Was followup of patients sufficiently long and complete (eg >80%)?	Yes	Yes	Yes	Yes

(C) Validity of study results (presence of all 4 factors = good; presence of above 3 factors = fair; presence of above 2 factors = poor; presence of above 1 or less factors = study should be excluded from further review)	Fair	Fair	Fair	Good

Adapted from Levels of Evidence used for the review of Resuscitation Science for 2010 from C2010 Consensus Process
(http://www.heart.org/idc/groups/heart-public/@wcm/@private/@ecc/documents/downloadable/ucm_308199.pdf).