Review Article

The Mortality in Emergency Department Sepsis Score as a Predictor of 1-Month Mortality among Adult Patients with Sepsis: Weighing the Evidence

Table 4

Area under the ROC curve for MEDS score and respective biomarkers for prediction of mortality.

Area under the ROC curve (95% CI)
Hermans et al., 2012 [23]Lee et al., 2008a [24]Vorwerk et al., 2009 [26]Zhao et al., 2013 [25]
28-day mortality5-day mortality6- to 30-day mortality28-day mortality28-day mortality

MEDS score0.81 (0.73–0.88)0.890.820.82 (0.78–0.87)b0.78 (0.73–0.83)
C-reactive protein0.68 (0.58–0.78)0.680.640.66 (0.61–0.72)
Procalcitonin0.760.730.68 (0.63–0.74)
Lactate0.75 (0.6–0.9)0.62 (0.54–0.7)
Interleukin-60.69 (0.64–0.74)
MEDS + procalcitonin0.81 (0.77–0.86)

95% CI not available.
bAbbreviated MEDS score.
CI: confidence interval; MEDS: Mortality in Emergency Department Sepsis, ROC: receiver operating characteristic.