Extrahepatic 25-Hydroxylation of Vitamin D3 in an Engineered Osteoblast Precursor Cell Line Exploring the Influence on Cellular Proliferation and Matrix Maturation during Bone Development
Figure 1
Alkaline phosphatase activity (ALP) of osteoblast precursor OPC1 and MC3T3-E1 after 10 days in culture after being treated with or without vitamin D3 (BM− control). After 10 days there was not a significant effect on ALP activity between treatment with either 1 μM or 10 μM vitamin D3; however, there was an overall statistically significant increase in ALP activity between vitamin D3 treated cultures and controls.
