Review Article
Fetal Nucleic Acids in Maternal Circulation: A Genetic Resource for Noninvasive Prenatal Diagnosis
Table 1
Risk of miscarriage in invasive methods of PND.
| | Invasive test for prenatal diagnosis | Sample taken through | Gestation time at which procedure performed | Risk of miscarriage* |
| | Chorionic villus Sampling (CVS) or choriocentesis | Abdomen or vagina | 11–13 weeks | <1% (1.9) | | Amniocentesis or amniotic fluid test (AFT) | Abdomen | 9–18 weeks | <1% (1.4) | | Cordocentesis or percutaneous umbilical cord blood sampling (PUBS) | Abdomen | 18–20 weeks | ~2% |
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*Procedure risk of miscarriage increases with advancement in maternal age.
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