Research Article
Novel ZrOCl2·8H2O-Catalysed One-Pot Multicomponent Synthesis of 9,10-Dihydro-8H-benzo[a]xanthen-11(12H)-one Derivatives
Table 2
Synthesis of xanthenes in the presence of ZrOCl2·8H2O.
| | Entry | R | Product | Time (h) | Yielda (%) |
| | 1 | C6H5 | 4a | 1 | 92 | | 2 | p-CH3C6H4 | 4b | 2 | 85 | | 3 | 3-CH3-4-CH3-C6H3 | 4c | 3 | 82 | | 4 | p-CH3OC6H4 | 4d | 2 | 85 | | 5 | p-ClC6H4 | 4e | 1 | 95 | | 6 | p-NO2C6H4 | 4f | 1 | 96 | | 7 | o-NO2C6H4 | 4g | 1 | 90 | | 8 | p-ClC6H4 | 4h | 1 | 95 | | 9 | p-FC6H4 | 4i | 0.5 | 97 | | 10 | o-FC6H4 | 4j | 0.5 | 95 | | 11 | p-CF3C6H4 | 4k | 0.5 | 97 | | 12 | p-(C6H5)C6H4 | 4l | 1 | 91 | | 13 | CH3CH2 | 4m | 4 | 75 | | 14 | 2-Thiophene | 4n | 5 | 80 | | 15 | 2-Furan | 4o | 5 | 82 |
|
|
Isolated yield.
|
