Research Article

Evaluation of Nonradiative Clinical Imaging Techniques for the Longitudinal Assessment of Tumour Growth in Murine CT26 Colon Carcinoma

Table 3

Comparison of MRI and US techniques to image mice bearing CT26 tumours.

MethodSpatial resolution (mm)Smallest detectable tumour (volume mm3)Analysis time (min)Main advantagesMain disadvantages

MRI0.123 14.4715(i) Real 3D volume
(ii) Anatomic information
(iii) Complementary data, functional information
(i) Expertise needed
(ii) Duration of data analyses
(iii) Operating cost

US0.1004.19<5(i) User friendly technique
(ii) Volume can be
 measured directly
(i) Volume estimation
(ii) Hairless mouse or
 shaved zone of
observation needed
(iii) Poor resolution