In Vitro Characterization of Valproic Acid, ATRA, and Cytarabine Used for Disease-Stabilization in Human Acute Myeloid Leukemia:
Antiproliferative Effects of Drugs on Endothelial and Osteoblastic Cells and Altered Release of Angioregulatory Mediators by Endothelial Cells
Figure 6
The relative ratio of cell proliferation versus mediator release from HUVECs after VPA treatment. The proliferation of HUVECs after 0.6 mM VPA treatment was reduced to 71% of drug-free controls, and the figure shows the relative ratio values of proliferation after 0.6 mM VPA treatment versus the concentration of various soluble mediators measured in HUVEC cultures after 0.6 mM VPA treatment.
