International Scholarly Research Notices

Research Article

Cognitive Impairment in Relapsing Remitting and Secondary Progressive Multiple Sclerosis Patients: Efficacy of a Computerized Cognitive Screening Battery

Table 5

(a) Mean scores (SD) of RRMS, SPMS, and controls on neuropsychological tests. (b) Effect sizes for differences between controls and MS subgroups (RRMS, SPMS). For Cohen’s and Hedges’ , an effect size of 0.2 to 0.3 might be a “small” effect, around 0.5 a “medium” effect and 0.8 to infinity, a “large” effect.
(a)
 RRMSSPMSControls
Tmta51.894 (19.549)63.436 (16.527)37.645 (12.547)
Tmtb97.543 (39.400)141.537 (41.787)79.646 (22.946)
Vfsem43.240 (10.413)36.967 (10.950)47.419 (8.865)
Vfphon29.340 (12.327)21.800 (9.393)34.871 (9.552)
Compmem90.940 (9.851)83.300 (9.675)97.903 (11.915)
Psyspeed135.520 (26.301)103.267 (27.875)148.387 (24.204)
Reactime827.360 (185.026)960.433 (143.748)618.516 (93.790)
Compatt15.180 (10.435)19.733 (9.755)13.129 (6.820)
Cognflex26.400 (22.707)14.200 (13.387)37.968 (15.070)
Procspeed39.580 (15.617)26.800 (10.387)40.613 (14.986)
Exfunction26.940 (22.835)15.733 (13.460)33.484 (16.442)
RRMS: relapsing-remitting multiple sclerosis; SPMS: secondary progressive multiple sclerosis; tmta: trail making test a; tmtb: trail making test b; vfsem: verbal fluency semantic; vfphon: verbal fluency phonological; compmem: composite memory; psyspeed: psychomotor speed; reactime: reaction time; compatt: complex attention; cognflex: cognitive flexibility; procspeed: processing speed; exfunction: executive function.
(b)
 RRMS versus SPMSRRMS versus ControlsSPMS versus Controls
TmtaHedges’ Hedges’ Hedges’
TmtbHedges’ Hedges’ Hedges’
VfsemHedges’ Hedges’ Hedges’
VfphonHedges’ Hedges’ Hedges’
CompmemHedges’ Hedges’ Hedges’
PsyspeedHedges’ Hedges’ Hedges’
ReactimeHedges’ Hedges’ Hedges’
CompattHedges’ Hedges’ Hedges’
CognflexHedges’ Hedges’ Hedges’
ProcspeedHedges’ Hedges’ Hedges’
ExfunctionHedges’ Hedges’ Hedges’
, , .
RRMS: relapsing remitting multiple sclerosis; SPMS: secondary progressive multiple sclerosis; CONTR: controls; tmta: trail making test a; tmtb: trail making test b; vfsem: verbal fluency semantic; vfphon: verbal fluency phonological; compmem: composite memory; psyspeed: psychomotor speed; reactime: reaction time; compatt: complex attention; cognflex: cognitive flexibility; procspeed: processing speed; exfunction: executive function.