Research Article

Investigations of the Biological Effects of Airborne and Inhalable Substances by Cell-Based In Vitro Methods: Fundamental Improvements to the ALI Concept

Figure 4

Flow geometry setting inside the ExpoCube including ALI cultures on a microporous membrane in a standard multiwell plate in combination with a stagnation flow setup. The ExpoCube has an exposure atmosphere enclosure that permits any direct contact between the exposure atmosphere and the culture medium.