Research Article

Investigations of the Biological Effects of Airborne and Inhalable Substances by Cell-Based In Vitro Methods: Fundamental Improvements to the ALI Concept

Table 1

Comparison of EC50 values as results from exposures with the improved ALI exposure procedure (ExpoCube) and from the prevalidation study (four partner labs).

EC50  ppm×h×mL/min×cm²
ExpoCubePrevalidation study*
UCLLCLs.d.

Formaldehyde102.778.566.45140.3871.55
Ozone29.6328.089.3641.1325.33

UCL: upper confidence limit (95%) from fitting.
LCL: lower confidence limit (95%) from fitting.
s.d.: standard deviation (partner labs from round robin study).
*See [15].