International Scholarly Research Notices

Research Article

The Sex Differences of Morphology and Immunology of SIRS of Newborn Wistar Rats

Table 1

Endotoxin, corticosterone, and sex hormones levels in the serum of 2-day-old male and female Wistar rats in two control groups and on the 1st day after LPS injection (Med: 25%–75%).


	Females		Males
	Control group	LPS 1	Control group	LPS 1

Endotoxin (eU/ml)	1.9 (0.5–3.3)	57^* (47.3–90.7)	0.5 (0.1–2.6)	33.5^*& (29.7–44.3)
Corticosterone (nmol/l)	122.3 (112–440)	436.3 (235.5–447.5)	215.1 (35.9–340)	351.3 (210.6–460)
Total testosterone (ng/ml)	0.2 (0.2-0.3)	0.4 (0.2–0.5)	0.3 (0.1–3.3)	1.7 (1.5–2.1)
Estradiol (pg/ml)	32.9 (32–34.5)	19.5 (13.2–21.8)	22.2^# (20.2–24.6)	8.4^* (6.7–21.5)
Progesterone (ng/ml)	1.2 (0.6–1.2)	0.5 (0.2–0.8)	0.8 (0.7-0.8)	0.5 (0.3–0.8)
ALT (eU/l)	22 (13–41)	107^* (89–222)	50.5 (29–74)	102^* (52–174)
AST (eU/l)	264 (217–422)	512 (244–685)	197 (132.5–371.5)	294 (179–343)

Med: median, 25%–75%: interquartile range, LPS 1: the 1st day after LPS injection, ^*differences which are statistically significant as compared with the corresponding control group, ^&differences which are statistically significant between males and females after LPS injection, and ^#differences which are statistically significant between control groups of males and females.