Research Article
Development and Statistical Optimisation of Buspirone Hydrochloride Buccoadhesive Films
Table 4
Diffusion kinetic profile of various formulations.
| | Kinetic profile of formulations | For Higuchi equation |
For Peppas
Korsmayer equation | For 1st order equation | For zero order equation | | | | | | | | | |
| | Desirability | 25.130 | 0.912 | 0.698 | 1.218 | −0.108 | 0.750 | −0.249 | 8.926 | 0.961 |
| | F1 | 44.862 | 0.801 | 0.230 | 1.794 | −0.214 | 0.907 | −0.492 | 15.27 | 0.039 | | F2 | 30.364 | 0.900 | 0.369 | 1.595 | −0.129 | 0.883 | −0.298 | 9.98 | 0.467 | | F3 | 28.391 | 0.988 | 0.462 | 1.487 | −0.102 | 0.955 | −0.235 | 9.450 | 0.676 | | F4 | 32.988 | 0.799 | 0.319 | 1.661 | −0.134 | 0.979 | −0.308 | 10.41 | 0.299 | | F5 | 26.614 | 0.975 | 0.417 | 1.494 | −0.082 | 0.968 | −0.188 | 8.856 | 0.659 | | F6 | 24.497 | 0.994 | 0.549 | 1.347 | −0.069 | 0.984 | −0.160 | 8.255 | 0.818 | | F7 | 30.028 | 0.970 | 0.456 | 1.518 | −0.131 | 0.903 | −0.301 | 9.958 | 0.626 | | F8 | 24.480 | 0.992 | 0.459 | 1.422 | −0.067 | 0.975 | −0.154 | 8.185 | 0.728 | | F9 | 22.350 | 0.985 | 0.603 | 1.261 | −0.057 | 0.983 | −0.132 | 7.558 | 0.849 |
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: release exponent, : correlation coefficient, : slope.
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