Research Article
Development and Statistical Optimisation of Buspirone Hydrochloride Buccoadhesive Films
Table 5
Formulation chart for optimized formulation.
| | Formulation code | Amount of drug (mg) | Total amount of polymer |
Amount of HPMC K15M |
Amount of Eudragit RL-100 |
Amount of permeation enhancer |
Amount of plasticizer | Solvent | | | | | | Na-lauryl sulphate | PEG 400 | Water | Alcohol | | (%) | (mg) | (%) | (mg) | (%) | (mL) | (%) | (mL) | (mL) | (mL) |
| | OF1 | 50 | 400 | 75 | 300 | 25 | 100 | 5 | 0.024 | 20 | 0.08 | 30 | 20 | | OF2 | 50 | 350 | 70 | 245 | 30 | 105 | 5 | 0.021 | 20 | 0.07 | 24.5 | 17.5 |
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