Research Article
Development and Statistical Optimisation of Buspirone Hydrochloride Buccoadhesive Films
Table 6
Physicochemical parameters of optimized formulations.
| | Formulations | Surface pH* | Swelling studies | Weight uniformity (mg)* | Thickness (µm)* | Folding endurance* | Drug content* | Bioadhesion strength* (g) |
| | OF1 | 6.2 ± 0.03 | 1.21 | 413.21 ± 2.66 | 292.52 ± 1.65 | 144 ± 3 | 98.42 ± 1.36 | 9.93 ± 0.34 | | OF2 | 6.4 ± 0.04 | 1.17 | 353.47 ± 3.48 | 259.69 ± 2.23 | 138 ± 4 | 98.07 ± 0.86 | 9.21 ± 0.58 |
|
|
Data represents mean ± SD, .
|
