Research Article
Development and Statistical Optimisation of Buspirone Hydrochloride Buccoadhesive Films
Table 7
Comparison of various dependent variables of optimized formulations.
| | Parameters | Total Amount of Polymer | Percentage Of HPMC K15M |
(h) |
(h) | Diffusion at 3 h | Diffusion at 6 h | Diffusion at 9 h |
| | Codes | | | | | | | |
| | Desirability | | | 5.25 | 9.28 | 33.18 | 55.60 | 78.01 |
| | Predicted OF1 | 400 | 75 | 4.43 | 11.30 | 38.68 | 60.63 | 70.63 | | Predicted OF2 | 350 | 70 | 4.43 | 11.40 | 39.04 | 60.14 | 70.20 | | Experimental OF1 | 400 | 75 | 4.12 | 8.56 | 45.56 ± 1.78 | 65.78 ± 2.42 | 80.42 ± 2.44 | | Experimental OF2 | 350 | 70 | 4.41 | 9.23 | 42.87 ± 1.54 | 63.45 ± 1.84 | 77.84 ± 2.20 |
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