International Scholarly Research Notices

Research Article

Antihyperlipidemic Activity of Aloe succotrina in Rats: Possibly Mediated by Inhibition of HMG-CoA Reductase

Table 2

Effect of dried pulp of Aloe succotrina leaves on relative liver and heart weight of HFD-induced hyperlipidemic rats.


Group number	Treatment (p.o.)	Dose (kg⁻¹)	Number of animals	Relative organ weight
Group number	Treatment (p.o.)	Dose (kg⁻¹)	Number of animals	Liver weight	Heart weight

1	Vehicle (1% w/v CMC)	10 mL	6
2	Vehicle (1% w/v CMC) + HFD	10 mL	6
3	Atorvastatin + HFD	10 mg	3
4	Aloe succotrina + HFD	100 mg	5
5	Aloe succotrina + HFD	200 mg	5

Relative weight = (organ weight/body weight) × 100. Values are in Mean ± SEM; data were analyzed by one-way ANOVA followed by Tukey-Kramer multiple comparison test.
F (4, 20) = 8.271; (for relative liver weight).
F (4, 20) = 0.747; (for relative heart weight).
^### as compared to vehicle treated control; ^a as compared to HFD treated control.