International Scholarly Research Notices

Research Article

Antihyperlipidemic Activity of Aloe succotrina in Rats: Possibly Mediated by Inhibition of HMG-CoA Reductase

Table 5

Effect of dried pulp of Aloe succotrina leaves on body weight of fructose-induced hyperlipidemic rats.


Group number	Treatment (p.o.)	Dose (kg⁻¹)	Body weight (g)
Group number	Treatment (p.o.)	Dose (kg⁻¹)	Week 0	Week 1	Week 2	Week 3	Week 4

1	Vehicle (1% w/v CMC)0	10 mL
2	Vehicle (1% w/v CMC) + fructose (25% w/v)	10 mL
3	Atorvastatin + fructose (25% w/v)	10 mg
4	Aloe succotrina + fructose (25% w/v)	100 mg
5	Aloe succotrina + fructose (25% w/v)	200 mg

in each group. Values are in Mean ± SEM; data was analyzed by one-way ANOVA followed by Tukey-Kramer multiple comparison test.
F (4, 25) = 0.95; (for fructose treated control from week 0 to week 4).
F (4, 25) = 0.19; (comparison among various groups at week 1).
F (4, 25) = 0.18; (comparison among various groups at week 2).
F (4, 25) = 0.49; (comparison among various groups at week 3).
F (4, 25) = 0.49; (comparison among various groups at week 4).