International Scholarly Research Notices

Research Article

Antihyperlipidemic Activity of Aloe succotrina in Rats: Possibly Mediated by Inhibition of HMG-CoA Reductase

Table 6

Effect of dried pulp of Aloe succotrina leaves on relative liver and heart weight of fructose-induced hyperlipidemic rats.


Group number	Treatment (p.o.)	Dose (kg⁻¹)	Relative organ weight
Group number	Treatment (p.o.)	Dose (kg⁻¹)	Liver weight	Heart weight

1	Vehicle (1% w/v CMC)	10 mL
2	Vehicle (1% w/v CMC) + fructose (25% w/v)	10 mL
3	Atorvastatin + fructose (25% w/v)	10 mg
4	Aloe succotrina + fructose (25% w/v)	100 mg
5	Aloe succotrina + fructose (25% w/v)	200 mg

Relative weight = (organ weight/body weight) × 100.
in each group. Values are in Mean ± SEM; data was analyzed by one-way ANOVA followed by Tukey-Kramer multiple comparison test.
F (4, 21) = 4.742; (for relative liver weight).
F (4, 21) = 1.594; (for relative heart weight).
^## as compared to vehicle treated control; ^a as compared to fructose treated control.