International Scholarly Research Notices

Review Article

Oral Cavity as an Extragastric Reservoir of Helicobacter pylori

Table 7

Data regarding effects of anti-H. pylori therapy on dental plaque.


No.	Authors	Year	Method used to detect H. pylori	Sample size	Prevalence of H. pylori	Prevalence after anti-H. pylori therapy	Effect on H. pylori infection

1	Gao et al. [44]	2011	PCR-ureC and cagA genes	80 patients with H. pylori infection-37 treated with anti-H. pylori therapy and 43 treated with anti-H. pylori therapy and periodontal therapy		After 4 weeks-29.7% in gp A and 4.7% in gp B; after 1 year-43.2% in gp A and 18.6% in gp B	Eradication rate of gastric H. pylori. After 4 weeks-73% in gp A and 81.4% in gp B After 1 year-32.4% in gp A and 62.8% in gp B
2	Bago et al. [41]	2011	PCR-16S rDNA	56 patients with chronic periodontitis and gastric H. pylori positive	37.5% ()	0	Eradication rate in stomach was 76.2%
3	Zaric et al. [40]	2009	PCR	44 patients: 21 patients positive for H. pylori in subgingival dental plaque and gastric mucosa and 23 patients who were positive for H. pylori only in gastric mucosa-all 44 received only for H. pylori (triple) therapy		In G⁺O⁺t-66.7%	In the G⁺O⁺t group, only 47.6% showed eradication of gastric H. pylori compared to 87.4% in G⁺O⁻t
4	Gebara et al. [42]	2006	PCR-16S rDNA	30 dentate patients with gingivitis/periodontitis and H. pylori infection who received anti-H. pylori therapy	20% () in supra-gingival plaque and 26.6% () in sub-gingival plaque	30% in supra-gingival plaque and 46.7% in sub-gingival plaque
5	Gürbüz et al. [30]	2003	CLO test	75 dyspeptic patients of which 61 were H. pylori positive and also had H. pylori in dental plaque	90.7% (); 81.3% () had co-infection	100%
6	Suk et al. [45]	2002	PCR-cagA	Sixty-five patients with dyspeptic symptoms	Overall-43.1% (), 73.7% (28/38) among H. pylori positive patients	92.9%
7	Butt et al. [46]	2001	Smear cytology	82 patients positive for H. pylori in dental plaque: 27 received only anti-H. pylori therapy (gp 1); 25 received anti-HP therapy + periodontal therapy (gp 2); 30 received only periodontal therapy (gp 3)	100%	100% in gp 1; 16% in gp 2; 10% in gp 3
8	Miyabayashi et al. [43]	2000	PCR-ureA	47 patients with chronic gastritis or peptic ulcer-48.9% () were positive for oral HP and 38.3% () had HP in plaque		Oral prevalence at 4 weeks-31.9	At 4 weeks-91.6% of subjects negative for oral H. pylori were successfully eradicated of HP infection compared to 52.2% in oral H. pylori positive patients. At 2 years-95.8% of subjects negative for oral H. pylori were successfully eradicated of H. pylori infection compared to 69.5% in oral H. pylori positive patients