Review Article
A Review of In Vitro Drug Release Test Methods for Nano-Sized Dosage Forms
Table 2
Examples of IVIVC with nano-sized dosage forms in animal models.
| | Drug and dosage form | In vitro release set-up | In vivo studies | IVIVC type | Reference |
| | Indomethacin gelatin nanoparticles | Dialysis bags | Wistar Albino rats | Level A | [32] | | Silybin meglumine hollow-sphere mesoporous silica nanoparticles | Combination (USP I—dialysis bag) | Beagle dogs | Level A | [33] | Silybin 72-hour SLB and
PSNs (porous silica nanoparticles) | Combination (USP I—dialysis bag) | Beagle dogs | Level A | [35] | | Simvastatin nanostructured lipid carriers and nanoparticles | Dialysis bag | Balb/C mice | Level A | [34] | | Fenofibrate nanosuspension | USP I apparatus | Sprague Dawley rats | Level A | [36] | | Fenofibrate lipid matrix particles | In vitro lipolysis model | Sprague Dawley rats | Rank order | [37] |
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