Clinical Study

Targeted Screening for Latent TB Infection prior to Biologic Therapy to Improve Patient Safety and Reduce Costs: A Prospective Observational Study

Table 4

Risk stratification for patients with a normal chest X-ray and no additional risk factors for TB exposure (risk statistics derived from the BTS guidelines) [4].

Age group
(years)
Number of patientsTB risk adjusted ×5 for anti-TNF
effects/100 000
Risks of
prophylaxis/100 000
Risk/benefit
conclusion

15–341910278Observation
35–543420278Observation
55–744035278Observation
>75955278Observation