Research Article
Combined Phosphoproteomics and Bioinformatics Strategy in Deciphering Drug Resistant Related Pathways in Triple Negative Breast Cancer
Table 1
The IC50 ranking of twelve TNBC cell lines against four chemotherapy drugs.
| | IC50 ranking | Doxorubicin
IC50 (nM) | Docetaxel
IC50 (nM) | Gemcitabine
IC50 (nM) | Cisplatin
IC50 (nM) |
| | 1 | HCC1395 (5783) | HCC1187
no response | HCC1187
no response | HCC1187
no response | | 2 | MDA157 (1322) | MDA436
no response | MDA436
no response | MDA436
no response | | 3 | HCC1937 (841.7) | HS578T
no response | MDA231
no response | MDA231
no response | | 4 | MDA436 (840.1) | HCC38
(318634) | HCC1395
no response | HCC1395
no response | | 5 | MDA231 (644.6) | HCC1937
(253392) | MDA157
no response | MDA157
no response | | 6 | HCC70
(531.4) | HCC70
(253375) | HS578T
no response | HCC1937
(333854) | | 7 | HS578T
(454) | MDA231
(215645) | HCC1937
no response | HCC38
(232374) | | 8 | HCC1187 (413.9) | HCC1395
(197207) | HCC70
no response | HCC1806
(208994) | | 9 | BT20
(401.5) | MDA157
(160190) | BT20
(510.4) | BT20
(186719) | | 10 | HCC1806 (233.2) | BT20
(149325) | MDA468
(146) | MDA468
(59710) | | 11 | MDA468 (158.9) | MDA468
(2.378) | HCC38
(11.03) | HS578T
(46238) | | 12 | HCC38
(131.2) | HCC1806
(1.102) | HCC1806
(4.163) | HCC70
(30469) |
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