Research Article
Combined Phosphoproteomics and Bioinformatics Strategy in Deciphering Drug Resistant Related Pathways in Triple Negative Breast Cancer
Table 1
The IC50 ranking of twelve TNBC cell lines against four chemotherapy drugs.
| IC50 ranking | Doxorubicin IC50 (nM) | Docetaxel IC50 (nM) | Gemcitabine IC50 (nM) | Cisplatin IC50 (nM) |
| 1 | HCC1395 (5783) | HCC1187 no response | HCC1187 no response | HCC1187 no response | 2 | MDA157 (1322) | MDA436 no response | MDA436 no response | MDA436 no response | 3 | HCC1937 (841.7) | HS578T no response | MDA231 no response | MDA231 no response | 4 | MDA436 (840.1) | HCC38 (318634) | HCC1395 no response | HCC1395 no response | 5 | MDA231 (644.6) | HCC1937 (253392) | MDA157 no response | MDA157 no response | 6 | HCC70 (531.4) | HCC70 (253375) | HS578T no response | HCC1937 (333854) | 7 | HS578T (454) | MDA231 (215645) | HCC1937 no response | HCC38 (232374) | 8 | HCC1187 (413.9) | HCC1395 (197207) | HCC70 no response | HCC1806 (208994) | 9 | BT20 (401.5) | MDA157 (160190) | BT20 (510.4) | BT20 (186719) | 10 | HCC1806 (233.2) | BT20 (149325) | MDA468 (146) | MDA468 (59710) | 11 | MDA468 (158.9) | MDA468 (2.378) | HCC38 (11.03) | HS578T (46238) | 12 | HCC38 (131.2) | HCC1806 (1.102) | HCC1806 (4.163) | HCC70 (30469) |
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