Organocatalysis: Key Trends in Green Synthetic Chemistry, Challenges, Scope towards Heterogenization, and Importance from Research and Industrial Point of View
Table 3
Comparison among organometallic catalysts, enzyme catalysts, and organocatalysts.
Organometallic catalyst
Enzyme catalyst
Organocatalyst
Wide substrate scope; high catalytic activity; involving tedious process; potential heavy metal pollution
Limited substrate scope; high selectivity and catalytic activity; usually single enantiomer
Robust; inexpensive; readily available; nontoxic; inert toward moisture and oxygen; method especially attractive for the preparation of compound that do not tolerate metal contamination (pharmaceutical products)