Research Article

Evaluation of the Pattern of EPIYA Motifs in the Helicobacter pylori cagA Gene of Patients with Gastritis and Gastric Adenocarcinoma from the Brazilian Amazon Region

Table 2

Association between the presence or absence of the cagA gene and the histopathological findings of the study participants.

Histopathological findingcagA geneOR (95% CI)
Positive (%)Negative (%)

Degree of inflammation
 Mild39 (15.23)50 (39.06)3.57 (2.18–5.84)0.0001
 Moderate to intense217 (84.77)78 (60.94)
Neutrophil activity
 Mild51 (20)94 (73.44)11.11 (5.48–22.30)0.0001
 Moderate to intense205 (80)34 (26.56)
Metaplasia
 Mild39 (15.23)6 (4.69)3.65 (1.50–8.88)0.004
 Moderate to intense217 (84.77)122 (95.31)