Research Article
Nanoemulsion Based Hydrogel for Enhanced Transdermal Delivery of Ketoprofen
Table 7
Comparative permeation profile of different formulations.
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Values are expressed as mean ± SD (). CADP: cumulative amount of drug permeated; : enhancement ratio; LAE: local accumulation efficiency = ketoprofen retained into skin/ ketoprofen permeated through skin. ; Student’s -test was used to compare NG6 (optimized formulation) with drug solution, plain drug gel, and marketed formulation. ; Student’s -test was also used to compare N6 (plain nanoemulsion) with NG6 and no significant difference was found. |