Molecular Biology International

Research Article

Interleukin-6 c.-174G>C Polymorphism and Periodontitis in a Brazilian Population

Table 1

Clinical and demographic profile of the group case and control subjects regarding the periodontitis in the analyzed population sample from Vitória da Conquista, Brazil.


Variables	Periodontitis case	Periodontitis control	Odds ratio (raw)	CI 95%	value^*
	= 134	= 196
	(%)	(%)

Demographic data
Age
≥30 years	95 (70.9%)	100 (51.0%)	2.54	[1.60; 4.04]	<0.001
<30 years	39 (29.1%)	96 (49.0%)	1.00	[1.60; 4.04]	<0.001
Gender
Female	106 (79.1%)	154 (78.6%)	1.03	[0.60; 1.77]	0.907
Male	28 (20.9%)	42 (21.4%)	1.00	[0.60; 1.77]	0.907
Scholarship¹
<high school	95 (73.6%)	122 (62.6%)	1.67	[1.03; 2.72]	0.038
≥high school	34 (26.4%)	73 (37.4%)	1.00	[1.03; 2.72]	0.038
Smoking
Yes	28 (20.9%)	21 (10.7%)	2.20	[1.19; 4.07]	0.011
No	106 (79.1%)	175 (89.3%)	1.00	[1.19; 4.07]	0.011
Diabetes²
Yes	5 (3.8%)	3 (1.5%)	2.49	[0.58; 10.59]	0.203
No	128 (96.2%)	191 (98.5%)	1.00	[0.58; 10.59]	0.203
Cardiorespiratory diseases³
Yes	29 (21.6%)	40 (20.6%)	1.06	[0.62; 1.82]	0.823
No	105 (78.4%)	154 (79.4%)	1.00	[0.62; 1.82]	0.823
Signals and symptoms
Tooth mobility⁴
Yes	49 (36.6%)	31 (15.9%)	3.05	[1.81; 5.13]	<0.001
No	85 (63.4%)	164 (84.1%)	1.00	[1.81; 5.13]	<0.001
Gingival bleeding
Yes	90 (67.2%)	120 (61.2%)	1.29	[0.82; 2.05]	0.271
No	44 (32.8%)	76 (38.8%)	1.00	[0.82; 2.05]	0.271
Gingival sensitivity
Yes	110 (82.1%)	151 (77.0%)	1.37	[0.79; 2.37]	0.268
No	24 (17.9%)	45 (23.0%)	1.00	[0.79; 2.37]	0.268
Discomfort when chewing⁵
Yes	77 (58.8%)	84 (43.8%)	1.83	[1.17; 2.87]	0.008
No	54 (41.2%)	108 (56.2%)	1.00	[1.17; 2.87]	0.008

Observation loss: ¹scholarship: 6 losses (); ²diabetes: 3 losses (); ³cardiorespiratory diseases: 2 losses (); ⁴tooth mobility: 1 loss (); ⁵discomfort when chewing: 7 losses ().
^*Chi-square () and Fisher’s exact tests.