Research Article
Taste Masked Orally Disintegrating Pellets of Antihistaminic and Mucolytic Drug: Formulation, Characterization, and In Vivo Studies in Human
Table 1
Formulation design for ODPs containing A-HCL and C-DHCL.
| | Composition (mg) | P1 | P2 | P3 | P4 |
| | Ambroxol hydrochloride | 3 | 30 | 30 | 30 | | Cetirizine Dihydrochloride | 5 | 5 | 5 | 5 | | Kyron T-134 (polacrillin potassium) | 120 | 70 | — | 140 | | Eudragit EPO | 20 | 70 | 140 | — | | Mannitol | 55.24 | 55.24 | 55.24 | 55.24 | | Sorbitol | 27.66 | 27.66 | 27.66 | 27.66 | | MCC | 30 | 30 | 30 | 30 | | Kyron T-314 | 12 | 12 | 12 | 12 | | Sucralose | 0.2 | 0.2 | 0.2 | 0.2 | | Chocolate flavor | q.s | q.s | q.s | q.s | | Xanthum gum | 5% | 5% | 5% | 5% |
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