Research Article

Taste Masked Orally Disintegrating Pellets of Antihistaminic and Mucolytic Drug: Formulation, Characterization, and In Vivo Studies in Human

Table 2

Angle of repose, percentage of drug content, and disintegration time of taste masked ODPs formulations P1–P4.

PF-codeParticle size (m)Span valueAORDrug content (%)DT (sec)
A-HClC-DHCl

P17360.6224.72 ± 1.6793.82 ± 0.4090.92 ± 0.25714.33 ± 0.57
P27290.5926.08 ± 2.5394.91 ± 0.2093.01 ± 0.34416.67 ± 0.56
P37230.6722.62 ± 2.4096.18 ± 0.2697.22 ± 0.30115.00 ± 0.0
P47280.6325.19 ± 1.8898.09 ± .14698.18 ± 0.13612.33 ± 0.57

PF = pellet formulation, AOR = angle of repose, and DT = disintegration time.