Review Article

Evolution of New Variants/Mutants of JE Virus, Its Effect on Neurovirulence, Antigenicity, Host Immune Responses and Disease Transmission in Endemic Areas

Table 3

Japanese encephalitis virus genotypes isolated from different parts of South East Asia and other countries.

GenotypeLocationEpitopeMethod used JEV surveillanceReferences

GIJapanE327 Glu 20.2–21.2 8.5–9.9 Multiplex RT-PCR Mosquito based [256]
GIChina, Korea, Cambodia, Thailand, AustraliaprM and E glycoprotein genes RT-PCR Mosquito based[252]
GII Australia, Malaysia, IndonesiaprM and E glycoprotein genesRT-PCR Pigs[254]
GIIITaiwanE proteinMultiplex RT-PCR Mosquito based [255]
GI–IIIAsia and Australasia E176, 177, 227, 244, 264Amino acid sequencing Mosquito based[257]
GIIIWest Bengal India Envelope proteins Mac-ELISA and RT-PCR Human[2]
GIIINorthern India E176, 177, 227, 244, 264, 279 Gene sequencing Human[242]
GIII CQ11-66 strain Chongqing, China E-genes Nested PCR Human[251]
GIII Shanghai, China, Wuhan, Nepal, Taiwan, Japan, Philippines, Korea, Sichuan, YunanE-genesMultiplex RT-PCRHuman
GIVIndonesia-Malaysia region, IndonesiaSix AA substitutions Amino acid sequencing Mosquito based[257]
GVMalaysia China and South KoreaSix AA substitutions Amino acid sequencing Mosquito based [257]
GVSingapore, Australia Structural genes Nucleotide and AA sequencing Mosquito based [258]
GVJapanStructural genesNucleotide sequencingMosquito based [253]