Research Article
High-Performance Liquid Chromatography Determination of Meloxicam and Piroxicam with Ultraviolet Detection
Table 1
Intra-assay accuracy, precision, and assay linearity for meloxicam in plasma.
| | Intra-assay variability | | Concentration added (ng/mL) | Concentration measured (ng/mL) bearded dragon (mean ± SD) | RSD (%) | Concentration measured (ng/mL) pig (mean ± S.D.) | RSD (%) |
| | 15 | 15 ± 0.71 | 4.6 | 15 ± 0.21 | 1.4 | | 750 | 708 ± 28 | 4.0 | 757 ± 69 | 9.1 | | 1250 | 1156 ± 46 | 4.0 | 1149 ± 2.8 | 0.25 | | 3000 | 2982 ± 155 | 5.1 | 2990 ± 160 | 5.3 | | 7500 | 7528 ± 758 | 10.0 | 7300 ± 680 | 9.3 |
| | Assay linearity | | | Mean ± SD | RSD (%) | Mean ± SD | RSD (%) |
| | -intercept | 0.0037 ± 0.0004 | 11.3 | 0.0033 ± 0.0003 | 9.1 | | Slope | 0.0020 ± 0.0002 | 12.3 | 0.0021 ± 0.0002 | 9.5 | | 0.995 ± 0.0028 | 0.28 | 0.994 ± 0.0038 | 0.38 |
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SD: standard deviation; : number of samples; RSD: relative standard deviation.
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