Research Article

Identification of Unique miRNA Biomarkers in Colorectal Adenoma and Carcinoma Using Microarray: Evaluation of Their Putative Role in Disease Progression

Figure 4

(a)—(A) We identified MB gene as the differentially expressed target in colon adenoma and carcinoma that was under the control of miR-135b. (B) MB was upregulated in adenoma and downregulated in carcinoma, respectively. (C) The expression of MB was correlated with the inverse expression pattern of miR-135b in adenoma and carcinoma. (b) Myoglobin interaction network in colon carcinoma. The interaction partner of Myoglobin is represented along with the functional role they represent in colorectal cancer.
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(a)
526075.fig.004b
(b)