Research Article

Influence of Hydration Status on Changes in Plasma Cortisol, Leukocytes, and Antigen-Stimulated Cytokine Production by Whole Blood Culture following Prolonged Exercise

Table 2

24 h cytokine production in response to in vitro antigen stimulation of whole blood collected before, after, and 2 h after exercise in euhydrated and dehydrated trials.

Euhydrated trialDehydrated trialStatistics
Before exerciseAfter exercise2 h after exerciseBefore exerciseAfter exercise2 h after exercise

IL-1 (pg/mL)0.40 (0.11–0.76)0.22 (0.07–0.38)0.25 (0.01–0.56)0.27 (0.02–0.56)0.22 (0.08–0.38)0.19 (0.07–0.32)
IL-1 (pg/mL)1.80 (0.78–3.42)2.50 (1.35–4.21)1.81 (1.12–2.71)1.95 (0.74–4.02)1.73 (0.63–3.59)1.38 (0.53–2.69)
IL-2 (pg/mL)8.01 (2.45–22.5)6.93 (2.44–17.3)4.80 (1.82–10.9)5.56 (1.37–17.2)4.31 (1.19–11.9)3.23 (1.16–7.30)
IL-4 (pg/mL)0.65 (0.16–1.14)0.73 (0.34–1.11)0.86 (0.27–1.44)0.58 (0.25–0.92)0.68 (0.32–1.04)0.55 (0.31–0.79)
IL6 (pg/mL)9.45 (3.47–23.5)10.8 (4.80–22.8)4.24 (1.70–9.16)8.54 (3.04–21.5)8.81 (3.13–22.3)4.05 (1.22–10.47)Main effect of time
,
Observed power
IL-10 (pg/mL)0.43 (0.09–0.88)0.77 (0.57–1.01)0.42 (0.16–0.73)0.40 (0.11–0.78)0.59 (0.34–0.90)0.38 (0.15–0.66)Main effect of time
,
Observed power
IFN- (pg/mL)0.76 (0.18–1.63)0.58 (0.17–1.14)0.48 (0.02–1.13)0.87 (0.26–1.79)0.45 (0.05–1.00)0.52 (0.16–1.00)
TNF- (pg/mL)2.68 (1.04–5.62)2.24 (1.38–3.43)2.40 (1.17–4.32)2.36 (0.77–5.36)2.12 (0.78–4.49)1.95 (0.80–3.83)

Data are presented as geometric means (95% CI).