Research Article
The Region Centromeric to HLA-C Is a Key Region for Understanding the Phenotypic Variability of Psoriatic Arthritis
Table 2
Distribution of the main genetic markers according to the articular patterns defined in the study. Psoriatic arthritis population: 110.
| | Marker | Oligoarthritis (%) | Polyarthritis (%) | Axial disease (%) | values |
| | 06 | 22 (52.4) | 12 (40) | 18 (47.4) | NS | | MICA-A9 | 27 (64.3) | 17 (56.7) | 22 (57.9) | NS | | 07 | 25 (59.5) | 4 (13.3) | 14 (36.8) | | | 04 | 5 (12) | 4 (13.3) | 5 (13.1) | NS | | HLA-B27 | 10 (23.8) | 4 (13.3) | 22 (57.9) | | | TNF-238A | 6 (14.3) | 5 (16.7) | 8 (21) | NS | | TNF-238G | 34 (81) | 25 (83.3) | 29 (76.3) | NS | | TNF-308A | 12 (28.6) | 9 (30) | 12 (31.6) | NS | | TNF-308G | 28 (66.7) | 21 (70) | 25 (65.8) | NS | | MICA-A5.1 | 9 (21.4) | 17 (56.7) | 12 (31.6) | |
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OR 4.1 (1.8–9.3). OR 5.7 (2.4–13.6). OR 3.7 (1.5–8.8). NS: nonsignificant. Note: significant values represent intergroup comparisons.
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