Research Article

Anticancer Activity of Tabernaemontana coronaria against Carcinogen Induced Clear Cell Renal Cell Carcinoma

Table 3

Effect of T. coronaria on DEN and Fe-NTA induced depletion of superoxide dismutase, catalase, glutathione peroxidase, and glutathione S transferase in kidney.

ParticularsSuperoxide dismutaseCatalase Glutathione peroxidaseGlutathione S transferase

Control
DEN + Fe-NTA
DEN and Fe-NTA + 200 mg/kg T. coronaria
DEN and Fe-NTA + 400 mg/kg T. coronaria
T. coronaria alone (200 mg/kg)
T. coronaria alone (400 mg/kg)

Values are expressed as mean ± SD ( ).
Values not sharing the common superscript (a–d) differ significantly (DMRT).
SOD—unit/mg protein.
CAT—μ moles of H2O2 consumed/min/mg protein.
GPx—μg of glutathione consumed/minute/mg protein.
GST: moles of CDNB conjugated/min/mg protein.