Research Article
Efficient Electrochemical N-Alkylation of N-Boc-Protected 4-Aminopyridines: Towards New Biologically Active Compounds
Table 3
Dialkylation reaction of 4-aminopyridine with -BuOK in DMSOa.
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| 1 mmol of 4AP in 2 mL of anhydrous DMSO, at rt, under N2. Then 2 mmol of -BuOK were added, followed by 2 mmol of halide after 20 min. The reaction was kept under stirring for 4 h. bAll the yields are in isolated products. | ||||||||||||||||||||||||
