Review Article
The Membrane Associated RING-CH Proteins: A Family of E3 Ligases with Diverse Roles through the Cell
Table 1
List of potential targets of MARCH9 identified in a SILAC experiment.
| Potential target of MARCH9 | Known function |
| PTPRA | Receptor tyrosine phosphatase | PTPRJ (CD148) | Receptor tyrosine phosphatase | PTPRF | Receptor tyrosine phosphatase | HLA-DQA | Present of processed antigens to T cells | HLA-DQB | Present of processed antigens to T cells | SLAM (CD150) | A self-ligand costimulatory receptor Receptor that recognizes Gram-negative bacteria Regulates the macrophage-killing machinery in phagosomes | ILT-2 (CD85j/LIR-1/LILRB1) | NK cell inhibitory receptor | FCRL2 | Fc receptor related molecule | Plexin C1 (CD232) | Inhibitor of integrin-mediated adhesion of DCs | VAMP8 | SNARE involved in endocytic vesicle fusion | TMEM2 | Involved in myocardial and endocardial morphogenesis | TRAIL-R1 | Immune surveillance |
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