International Scholarly Research Notices

Research Article

Rapid Detection of Rifampicin and Isoniazid Resistant Mycobacterium tuberculosis Using Genotype MTBDRplus Assay in Nepal

Table 7

Pattern of multiple gene mutations observed in MDR TB isolates using Genotype MTBDRplus assay.
Pattern of gene mutations in MDR-TB strainsNumber of isolates (%) ()
rpoB MUT3, rpoB WT8, katG MUT1, katG WT 14 (50)
rpoB MUT3, rpoB WT8, katG WT 1 (3.5)
rpoB WT8, katG MUT1, katG WT 2 (7.1)
rpoB MUT3, inhA MUT1, inhA WT1 1 (3.5)
rpoB WT7, katG WT 1 (3.5)
rpoB WT2, rpoB WT3, katG MUT1, katG WT 1 (3.5)
rpoB WT3, rpoB WT4, katG MUT1, katG WT 1 (3.5)
rpoB MUT1, rpoB WT3, rpoB WT4, katG MUT1, katG WT 5 (17.8)
rpoB MUT1, katG MUT2, katG WT 1 (3.5)
rpoB WT7, katG MUT1, katG WT 1 (3.5)
*MDR: multi-drug resistant.