Research Article

Development and Validation of Stability Indicating RP-HPLC Method for Estimation of Satranidazole from Its Formulation

Table 7

Results of forced degradation studies.

Degradation mechanismSTZ main peak retention time (min)Degradation peak retention time (min)

Acid hydrolysis4.3783.991
Base hydrolysis4.3693.228 and 3.383
H2O2 oxidation4.266No peak
UV radiation4.273No peak
Heat 4.30No peak