Research Article

Genetic Variants in the SORL1 Gene Are Associated with Age at Onset of Alzheimer Disease: A Survival Analysis

Table 2

Top 6 SNPs associated with the age at onset of Alzheimer’s disease using the logrank test.

SNPPositionA1aMAFbHWEcLogrank-alldLogrank-maleeLogrank-femalef

rs1784934121467284C0.360.350.2880.0400.96
rs676759121488556G0.400.490.1540.0080.933
rs560573121490175T0.390.590.1760.00770.836
rs593769121493294C0.390.840.1520.00770.933
rs11218313121512162G0.090.380.1850.03170.89
rs17125558121003094T0.030.710.07150.7580.039

aMinor allele; bminor allele frequency; cHardy-Weinberg equilibrium value; d value was based on logrank test for the whole sample; e value was based on the logrank test for the males; f value was based on the logrank test for the females.