Association of IL10-1082 and IFN-γ+874 Polymorphisms with Cervical Cancer among Tunisian Women
Table 4
Frequency distribution of the IFN-γ+874, IL-10-1082 genotypes among cases and controls and risk analysis for cervical cancer.
SNP
Genotype
Controls (%)
Cases (%)
OR (95% CI)
value
IFN-γ+874 T>A
T/T
64 (40)
32 (26.23)
0.53 (CI = 0.31–0.92)
0.015
T/A
68 (42.5)
65 (53.27)
1.54 (CI = 0.93–2.55)
0.072
A/A
28 (17.5)
25 (20.5)
1.22 (CI = 0.64–2.31)
0.524
Carrier A
96 (60)
90 (73.77)
1.88 (CI = 1.09–3.24)
0.015
IL-10-1082 G>A
G/G
34 (21.25)
19 (15.6)
0.68 (CI = 0.35–1.32)
0.226
G/A
108 (76.5)
81 (66.4)
0.95 (CI = 0.56–1.62)
0.844
A/A
18 (11.25)
22 (18)
1.74 (CI = 0.84–3.59)
0.105
Carrier A
126 (87.75)
103 (84.4)
1.46 (CI = 0.76–2.85)
0.226
SNP: single nucleotide polymorphism; OR: odds ratio; nominal value of comparison; : no significant association; degree of freedom = 1. Values in bold are statistically significant at the 5% level.
