Development and Validation of a Novel RP-HPLC Method for Estimation of Losartan Potassium in Dissolution Samples of Immediate and Sustained Release Tablets
Table 5
Results of Accuracy study.
Concentration Levels (%)
Areaa
Weight Spiked in mg
Weight Recovered in mg
Accuracy (%)
Mean
S.D.
% R.S.D.
80
3253.93481
40
39.69
99.23
98.69
0.697
0.71
3243.92433
40
39.57
98.92
3210.32104
40
39.16
97.90
100
4011.84668
50
48.94
97.87
98.30
0.704
0.72
4062.57153
50
49.56
99.11
4013.37207
50
48.96
97.91
120
4851.41895
60
59.18
98.63
98.64
0.301
0.30
4867.05420
60
59.37
98.95
4837.47510
60
59.01
98.35
S.D.: Standard deviation; R.S.D.: Relative standard deviation.
aAverage of three determinations.
