Research Article

Development and Validation of a Novel RP-HPLC Method for Estimation of Losartan Potassium in Dissolution Samples of Immediate and Sustained Release Tablets

Table 6

Results of intermediate and intraday precision.

ReplicatesDay 1 (area)Day 2 (area)Column I (area)Column II (area)

Area 14008.947024022.123014067.211344054.66455
Area 23986.295904006.956333956.543674036.49724
Area 33946.116463977.667543998.435543986.98756
Area 44029.718753989.079864009.469833992.43927
Area 54052.514404044.435324032.443564049.87234
Area 64025.624514065.124333988.544373995.05438

Average4008.202844017.564404008.774724019.25256
Standard deviation37.59033.22837.99931.095
RSD0.940.830.950.77

Average4012.883624014.01364
Standard deviation32.74732.157
RSD0.820.80

RSD: relative standard deviation.