Effects of 3-day treatment with M. macrophylla extracts combined or not with ICI 182,780 on the uterine wet weight (a), total protein levels in uterine (b), uterine epithelial height (c), and microphotographs (d). animals treated with the vehicle (OVX); animals treated with estradiol benzoate at 0.75 μg/kg BW; animals treated with the dichloromethane extract of M. macrophylla; animals treated with the methanol extract of M. macrophylla. , , and compared with control; , , and compared with the same dose of each substance without ICI 182,780. Lu: lumen; En: Endometrium; St: Stroma.