Research Article

Microwave Assisted Solvent-Free Synthesis of Some Imine Derivatives

Table 2

The optimization of classical conditions for compound 1a.

Classical method
Time (min)Yield (%)Reaction conditions

3064Reflux
6073Reflux
12076Reflux
24075Reflux
1300*74Reflux

Procedure: 1 mmol aldehyde (10 mL of ethanol) and 1 mmol amine (10 mL of ethanol) are mixed a balloon and then boiled under reflux on a hot plate.
*300 min (heated) + 1000 min (unheated).