Journal of Critical Care Medicine

Clinical Study

Refractory Status Epilepticus: Experience in a Neurological Intensive Care Unit

Table 3

AEDs administered for management of RSE.
Drug   
No. (%)		Dose used  
Lowest-Highest
Coma induction  
 Midazolam55 (87.3)0.0006–0.1‡
 Propofol28 (44.4)0.2–
 Thiopental3 (4.8)1–
AEDs  
 Levetiracetam78 (97.5)1000–
 Phenytoin67 (83.8)250–
 Topiramate63 (78.8)50–
 Valproate62 (77.5)450–
 Phenobarbital39 (48.8)150–
 Other*54 (67.5) 
Carbamazepine, lamotrigine, pregabalin, vigabatrin, and gabapentin.
‡mg/kg/hour.
mg/kg.
mg/day.
AED: antiepileptic drugs; RSE: refractory nonconvulsive status epilepticus.