Research Article

Fast Stability Indicating UPLC Method for Quantitative Analysis of Dronedarone in Pharmaceutical Dosage Form: Force Degradation Study

Table 6

Result of robustness study.

ParameterMean % RSDMean area% RSD

Flow rate
0.361.560.102402180.27
0.401.520.142324370.24
0.441.490.122204450.28

Mobile phase composition (buffer : methanol)
(38 : 62)1.410.142173520.34
(40 : 60)1.520.242324160.27
(42 : 58)1.580.112459380.26

Column oven temperature
25°C 1.610.212484750.39
30°C1.520.282323870.32
35°C1.390.172128680.21