Research Article
Tissue Taurine Depletion Alters Metabolic Response to Exercise and Reduces Running Capacity in Mice
Table 2
The changes in metabolite and glycogen levels in gastrocnemius muscle and liver before and after exercise in WT and TauTKO mice.
| | | | Muscle ATP (mmol/g wt) | Muscle lactate (nmol/g wt) | Muscle pyruvate (nmol/g wt) | Muscle luc/pyr | Muscle glycogen (mg/g wt) | Hepatic glycogen (mg/g wt) |
| | WT | Rest | 2.99 ± 0.053 (5) | 62.3 ± 6.65 (6) | 1.03 ± 0.13 (6) | 77.6 ± 15.8 (6) | 1.35 ± 0.098 (7) | 40.4 ± 8.09 (7) | | Run | 2.96 ± 0.21 (5) | 68.6 ± 6.61 (5) | 1.25 ± 0.22 (5) | 66.7 ± 14.8 (5) | 0.99 ± 0.16 (4)# | 6.78 ± 1.57 (7)# |
| | TauTKO | Rest | 3.26 ± 0.030 (5) | 83.4 ± 5.54 (5)* | 1.65 ± 0.20 (5) | 55.6 ± 5.45 (5) | 1.65 ± 0.22 (7) | 41.3 ± 6.90 (7) | | Run | 2.37 ± 0.31 (8)# | 70.3 ± 6.21 (8) | 0.78 ± 0.15 (8)# | 113 ± 20.0 (8) | 1.02 ± 0.22 (4)# | 8.83 ± 0.86 (7)# |
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Data are mean ± se. (). * versus WT, # versus before running.
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